Look at the whole dog
Energy, drinking, vomiting, diarrhea, abdominal comfort, breathing and willingness to take treats help determine urgency. A dog that refuses normal food but eagerly eats treats is different from a dog that refuses everything and seems unwell.
Common causes
Dental pain, nausea, gastrointestinal disease, pancreatitis, infection, fever, pain elsewhere in the body, stress and medication effects can all reduce appetite. Persistent anorexia should not be managed simply by rotating foods.
Related VetWel guides
Read dog diarrhea, dog vomiting and toxic foods.